Definitely, any more than 3 kids and you need to buy a van (or 4WD aka SUV for americans). Or so we thought... turns out that once they grow bigger, you need a 3-rows car anyway because if you jam 3 kids next to each other they fight like rabid cats.
At least in Europe the car seats are so wide and the benches so narrow that you can forget having 3 children in the back row. Also isofix is usually missing in the center “seat” which is typically smaller or even raised.
The only case that I have seen work is with two rear facing seats on the outer seats and a small/narrow front facing seat in the middle.
I wish manufacturers hadn’t killed off MPVs. Now we are stuck with older models with less to no hybrid/electric drivetrains at higher than new cost. Or getting a huge (for Europe standards) car or an gas guzzling van.
Edit: turns out that, in the Netherlands, a car seat in the center seat isn’t required if it doesn’t fit in your car. Only a raised seat is allowed if the kids are smaller than 135cm. But what about safety? Then the middle one won’t have a car seat.