Because of the size of the runtime, I'd rather use something like Solid.js which is smaller and faster.
https://hyperscript.org/docs/#async
It is dependency free and a bit under 30kb gz'd, which is roughly where jQuery is, and hyperscript is intended as a jQuery replacement. That's 35ms on emerging 4g, and in the browser cache after that. Probably not noticable for most situations.
Because of the size of the runtime, I'd rather use something like Solid.js which is smaller and faster.