Snatcher (by Hideo Kojima of Metal Gear Solid fame) is one of the best. Basically a Blade Runner-esque adventure/detective game with a bit of action too.

I started that one and it was actually pretty fun before my emu or something started bugging out.

Eventually I'll sit down and watch a let's play or find a good copy.

Lunar: The Silver Star and Lunar: Eternal Blue were great.

Dark Wizard! It remains one of my favorite games of all time and was [probably too] far ahead of its time. It's an open-world turn based battle strategy game with leveling units, multiple storylines to play through (with distinct heroes, persistent/leveling units, skill trees, evolution trees, etc), lots of secrets, and so on. It also has some great orchestral type music [1].

It holds up extremely well.

[2] - https://www.youtube.com/watch?v=WnLXQkkscy8

Sonic CD was always my favorite.

Best Sonic the Hedgehog game imo

The recent 2D Sonic that wasn’t truly made by Sega, Sonic Mania, would be my other contender.

Terminator is a notable original CD title, not a port unlike a lot of its cousins.