Might be related, but mouthwash use is correlated with a drop in systemic nitric oxide levels due to the negative impact on the oral microbiome. You can find a review here:
At Bristle (oral microbiome testing) we advocate against broad antimicrobial mouthrinses as they can negatively impact your oral health similar to how antibiotics cause dysbiosis in the gut.
https://pubmed.ncbi.nlm.nih.gov/35081826/
At Bristle (oral microbiome testing) we advocate against broad antimicrobial mouthrinses as they can negatively impact your oral health similar to how antibiotics cause dysbiosis in the gut.