I use container tabs, temporary tabs and the containerise extension to help manage things. I use it so there's stronger isolation between the websites I visit, and cookies are cleaned up when I close the browser.

That's on my main/personal profile.

I have separate profiles for work stuff, one for each client or organisation I work with. On those, I only access sites that are relevant to the organisation, and I have a lot fewer protections. I keep long sessions, I leave cookies in place, etc. It's a lot more convenient that way.