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subroutine
on Jan 22, 2022
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Strange DNA structures linked to cancer
Makes me wonder if this was discovered in mice engineered for inducible gene expression. TET/doxy mice are commonly used in experiments where you want to selectively turn on or off a particular gene.
https://pubmed.ncbi.nlm.nih.gov/27216914/
flobosg
on Jan 22, 2022
[–]
I might be wrong, but I think that TET enzymes and the Tet-Off/Tet-On system are not related.
Retr0
on Jan 22, 2022
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parent
[–]
Yeah TET here is ten-eleven translocation (
https://en.wikipedia.org/wiki/TET_enzymes
), not tetracycline (
https://en.wikipedia.org/wiki/Tetracycline-controlled_transc...
).
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https://pubmed.ncbi.nlm.nih.gov/27216914/