I'm dealing with something like this too. It's come up a lot while watching shows where some protagonist's friend turns psychotic and they suddenly must fight to survive. I keep thinking to myself, "just give up and let them kill you, it will be better that way!" I can't quite pinpoint the theme that seems to permeate all of these and how much of it is my own perspective versus some specific genre. I think of it a lot while watching The Future Diary, and also Higurashi: When They Cry.