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This is a good history on the effects and changing forms of treatment.

"The case-fatality rate varied from 20% to 60% and left most survivors with disfiguring scars. The case-fatality rate in infants was even higher, approaching 80% in London and 98% in Berlin during the late 1800s."

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1200696/




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