For folks who know any react I'd recommend react-three-fiber [1] as your entrypoint. It's ridiculously easy to get started. The creator (mlsarecmg on HN, I think), just came out with this tutorial today for beginners: https://twitter.com/0xca0a/status/1445409346305892353
It's paid but there's nearly endless free content as well between his twitter, the pmndrs discord, and the official docs [2].
I started using R3F and was able to put this [3] together, which is heavily inspired by Stripe design, in a couple weeks with some spare time. That is to say how easy it was and how highly I recommend the pmndrs suite for web 3D abstractions.
