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Receptor binding affinity can also increase too, or like Alpha did, further suppress interferon production. Lots of ways...



That reminds me of this scary preprint from January:

https://www.biorxiv.org/content/10.1101/2021.01.06.425392v3

"in vitro evolution enhancing binding by 600-fold provides guidelines towards potentially new evolving mutations with even higher infectivity" :/


I saw that yesterday and didn't post it because it was too scary lol




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