The friend/family perception is real and one thing, but really i think this silence creates yet more separation creating ever more loneliness.
Ultimately, my fear for lottery winners is akin to discovering cheat codes in early video games. Turning on "Infinite Money" in $GAME was great... until it quickly sucked all of the joy out of the game. The limited resource challenge disappeared. I don't know anyone who has won the lottery, but i'd be worried you risk creating that very same sentiment, except about life itself. Scary, should you not have another well-established and faithfully-held purpose.
I wouldn't worry about life itself. Life is not like a single-player games, the challenges thrown at you usually are not meant to be fun.
The more worrying part is the deteriorating social network. You go through life surrounded by friends and family, who are mostly in similar circumstances to you, face mostly similar problems. It's one of the biggest group-binding force. After a big windfall, you'll no longer have the same problems as other people in your life. That'll make it tricky to maintain relationships.
The cheat code feeling might only occur if your focus in life is earning lots of money. If you are instead pursuing to contribute something valuable in arts or sciences, a ton of money might just give you ease of mind and time to create something really worthwhile. Thinking about René Descartes, Charles Darwin and (as a more recent example) Jimmy Wales. It could indeed be that many of the former lottery winners ending up badly fell into the former camp.
Ultimately, my fear for lottery winners is akin to discovering cheat codes in early video games. Turning on "Infinite Money" in $GAME was great... until it quickly sucked all of the joy out of the game. The limited resource challenge disappeared. I don't know anyone who has won the lottery, but i'd be worried you risk creating that very same sentiment, except about life itself. Scary, should you not have another well-established and faithfully-held purpose.