Type 1 diabetes, rheumatoid arthritis, Crohn's disease, ulcerative colitis, lupus, multiple sclerosis; a whole grab-bag of fun.
These are also difficult diseases to treat – often involving biologics (large molecules administered by injection or IV). T1D is insulin, obviously, but the first big blockbuster medications in the space were Humira and Remicade, monoclonal antibodies, which are powerful immune-system suppressants but more selective (and therefore, relatively speaking, safer long-term) than systemic steroids like prednisone.
These are also difficult diseases to treat – often involving biologics (large molecules administered by injection or IV). T1D is insulin, obviously, but the first big blockbuster medications in the space were Humira and Remicade, monoclonal antibodies, which are powerful immune-system suppressants but more selective (and therefore, relatively speaking, safer long-term) than systemic steroids like prednisone.