Yeah, true. But you would only change it between songs, I guess, and only to the values you always use for that song, right? - This is what I would capture and use as a preset, preset change triggered by MIDI from the MultiFX unit.

I know some who change their settings during playing, but I wouldn't consider this as standard. Also, you can still add a real Pedal to a MultiFX Board if you really want to change its settings live. On the contrary, automatically changing the settings controlled by your DAW and triggered via MIDI into your MultiFX unit is also pretty common. You don't have to hassle with your Effects at all and can concentrate on playing, what you should, as you need to be absolutely on point.