I do like Cmd+c vs Ctrl+c on a mac. On linux I've changed my terminal to use Ctrl+Shift+c instead of Ctrl+c for ^C because I kept accidentally killing programs when trying to copy text with Ctrl+c which works in every app except terminals...
It goes way beyond that though: if command’s in a shortcut it pretty much guarantees that’s an application / system shortcut, which frees Ctrl to only deal with text control (and literal control codes in the shell).
And thus Option essentially only does alternate characters.
It’s not perfect, mind, for instance the number of keychords means emacs is annoying whether you leave meta on option or move it to command.
I configured my terminal to copy on mouse release. This allowed to keep Ctrl-C for killing processes while I use Ctrl-V to paste with Ctrl—Shift-V configured to send the original Ctrl-V.
I recently discover that if you remap Ctrl+C to Copy in a Linux terminal, you still get ^C when nothing is selected. It has made the experience so much better.
