Thanks. So what makes that happen in this case? Is it because internally the cell doesn’t recognize the protein? Or it does this for all proteins it makes? Does say some hemoglobin get transported to the cell surface?
Yes, the even healthy cells are constantly transporting protein fragments to the cell surface but the immune system learns to ignore these as it is developing.
In addition, B and T cells only detect fragments on the surface of active Dendric cells. Dendric cells become active in response to alternate and less specific indications of infection such as an unusually high amount of mRNA translation or families of protein that occur only in bacteria and viruses.
