Many video games are written in c#. This includes pretty much all games written using unity (the most popular 3d game engine) and fna (a very popular 2d framework).
But that's an apples/oranges comparison, isn't it? C# code in Unity games is predominantly high-level game behaviour / scripting. Most of the heavy lifting is done by Unity behind the scenes. So to me it's even more impressive that an emulator for a modern games console can be written in a 'managed' language.