not necessarily. if the body can somehow keep count, it may just replace the cells you remove. I'm not sure we know for certain either way yet.

My guess would be that that won't happen any more than limbs get regrown. Of course, my guess is pretty worthless. :)

Answer:

http://www.nytimes.com/2008/05/05/health/research/05fat.html...

> Losing or gaining weight affects only the amount of fat stored in the cells, not the number of cells.

BUT

> Every year [..] 10 percent of your fat cells die [...] and are replaced with new fat cells.

So, fat people aren't at a disadvantage by having far more cells.

your skin certainly knows where and when to (re)grow...