mod_xyz plugins were deprecated long ago because they are unstable. If you do a comparison you should compare fastcgi versus fastcgi, that is the standard way to run web applications. Running with mod should be faster because it's running the interpreter directly into the apache process but it's also making apache unstable.
mod_python was abandoned around a decade ago. It's crashing on python 2.7.
mod_perl was dropped in 2012 with the release of apache 2.4. It was kicked out of the project but continues to exist as a separate project (not sure if it works at all).
mod_python was abandoned around a decade ago. It's crashing on python 2.7.
mod_perl was dropped in 2012 with the release of apache 2.4. It was kicked out of the project but continues to exist as a separate project (not sure if it works at all).