The most popular blocker named 1Blocker is adding multiple rule lists, one for each of it’s categories (ads, trackers, regional rules, ...) to circumvent this limit. Its not a real problem.
I think the better way to put it is it is a real problem, but with a well known workaround. AFAIK, these slots needs to be pre-defined so you're still limited to number of lists that were defined at installation time.
This limitation prevent the model with traditional adblocker where extension and block lists are independently maintained by different parties (e.g. uBlock Origin/ABP + EasyList) so you're stuck with relying on extension maintainer to update their list or download another blocker app when the blocker become unmaintained (where in traditional model you could just subscribe to another list)