Not being in the field, I would term what I see in this story as a ‘bottom up’ approach to understanding genetics/molecular biology. More akin to applied sciences than medicine or health. This, for example, seems to be very important but it still leaves us with a jello jigsaw puzzle with 200 million pieces and probably far removed from immediate utility in health outcomes.
Then there’s the more clinically oriented approaches of looking at effects, trying to find associated genes/mutations whatever mechanisms exist in between to cause a desirable or undesirable outcome. I’d call that ‘top down’.
I’m sure the lines get blurred more every day, but is there a meaningful distinction into these and/or more categories that are working the problem from both ends? If so, are there associated terms of art for them?
Then there’s the more clinically oriented approaches of looking at effects, trying to find associated genes/mutations whatever mechanisms exist in between to cause a desirable or undesirable outcome. I’d call that ‘top down’.
I’m sure the lines get blurred more every day, but is there a meaningful distinction into these and/or more categories that are working the problem from both ends? If so, are there associated terms of art for them?