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mrDmrTmrJ
on Nov 30, 2020
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AlphaFold: a solution to a 50-year-old grand chall...
Excellent question. At somepoint, I think the only answer is, "have a bunch of different people run a bunch of experiments on the same protein."
The threshold for "real" in particle physics is +5 sigma. Which takes a lot of data.
dnautics
on Dec 1, 2020
[–]
you really can't compare stats like that. Those are independent, uncorrelated measurements. When you take RMSD measurements on a molecule they are not independent (for example, atoms near the core are less likely to be "inaccurate").
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The threshold for "real" in particle physics is +5 sigma. Which takes a lot of data.