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Getting from DNA structure from tissue samples is relatively straight forward. DNA -> RNA -> unfolded protein is basically one-to-one mapping in most cases. How protein functions depends on how it folds into itself. Once you solve protein folding, you can take DNA sample and see the structure of the molecule without working in lab using crystallography techniques.

Solving protein folding is huge, Nobel in chemistry scale achievement. It would be massive leap for biochemistry.

It seems that Deep Mind solved competition benchmark and made huge leap, but it's just partial solution that works on limited set.

After you have solved protein folding, there is still problem of solving chemical interactions between molecules accurately. Quantum chemistry is extremely compute intensive.




This is still for proteins that fold without chaperons, but I guess it does cover a lot.




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