Here's a random example. HMAC is frequently used in security protocols to generate more keys from a master key (for example, to generate temporary keys from a session key). The input to HMAC is (internally) padded with null bytes (<NUL>) before processing, so that for example "abc" and "abc<NUL><NUL><NUL>" will generate the same result. You may need to be aware of that padding when designing protocols that rely on HMAC, in order to avoid certain weaknesses. https://crypto.stackexchange.com/q/52161