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> Chloroquine and its derivatives were given to thousands, if not millions, of people for years. We know and understand the safety profile of this drug well. To think that all of a sudden it became more dangerous was silly and unreasonable.

Aspirin is one of the most widely used drugs and generally considered safe. But you should never give it to a kid with chickenpox, because doing so is a risk factor for developing Reye's Syndrome, a serious and potentially fatal disease.

It's not that aspirin "becomes more dangerous" in general, but it is more dangerous for those particular patients. And we don't really know why, either; but the data is clear on the correlation.

We don't yet know all the ways that the novel coronavirus makes people sick. Heck we don't even have a reliable inventory of possible symptoms yet.

So it's really not fair to pretend that it would be silly or unreasonable to suspect the possibility of some sort of negative correlation with a particular drug or class of drugs. This sort of thing happens all the time in medicine.



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