I've made it a rule to right click all chrome extensions icons and then set them to "This can read and change data > On www.example.com" on sites I really intend to use them. This prevents them from reading all sites but also prevents the annoyance of reloading the page every-time you need to use the extension. Also some extensions like Likepass inject some really ugly HTML into form fields (it also takes care of that)
It's a pretty useful feature that many people miss.
I've personally just switched from Chrome to Brave. Funnily enough, Chrome was causing my computer to seize all the time while Brave does not, even though it's still built on Chromium. But I took the opportunity to go ahead and clear out a number of extensions. Feels so much better. Your browser can really get cluttered over the years!
It's a pretty useful feature that many people miss.