Depends on the type of company you are trying to build. In the end, it will still going to be hard, but the crisis has pointed out some serious gaps across numerous industries that can be acted on. As a rule of thumb though, if everyone is talking about sector/tech/industry X being the next big thing, you are probably already a few months/years too late.

Reg cohort size, our cohorts are around 80-90 people with founders coming from a diverse set of industries and tech backgrounds. I agree with you though, it is ambitious and we are certainly looking for people who are courages enough to do it.