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One hypothesis to consider is the drastic decline in teen smoking rates. Nicotine is a powerful anti-psychotic. Smoking rates among the schizotypal are nearly double the rest of the population, even when controlling for common explanatory factors.

Social isolation, anxiety, depression, mild cognitive impairment and avoidant behavior are all signs of untreated schizophrenia. It's possible in the past that those with sub-clinical schizotypal personalities self-medicated with tobacco. Removing that would result in a sub-segment of the population becoming significantly less functional in a pronounced way.



I wonder how the decline of teen smoking follows the rise of other forms of stimulants, like caffeine, or other forms of nicotine consumption.




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