To get beyond a certain point in this game you will need a exact understanding of certain mechanics and advanced patterns. I doubt most people would come up with advanced patterns (e.g. how to build a well working main bus, or a conveyor balancer that works well) by themselves and learn that from the wiki.
If you purely stick to everything you learn ingame, you will probably hit a wall after 20 hours or so.
If you purely stick to everything you learn ingame, you will probably hit a wall after 20 hours or so.