I don't presume to know what that depends on, but wherever you go, in my experience, there seems to be a mix of job opportunities that are diploma-centric and skill-centric. What's more, the people I'm interested working with are generally in the latter category. So it's somewhat ironic, but the whole me-not-having-a-top-school-diploma thing works to my advantage by inadvertantly pinpointing the interesting opportunities.