Obama's aware of this. His major legislative achievement so far is a bill intended to promote access to health insurance (though most of the major provisions aren't yet in effect) --- on pretty much the same model as the Massachusetts law which others here have mentioned.
This is one of the things about Obamacare that I truly do not understand. I am a self-employed, type II diabetic. My health insurance premiums are massive. As I understand it, the law doesn't provide you free health care unless you are in the poverty range. For everyone else, it merely mandates that you buy insurance. How does adding a mandated expense on top of startup costs make entrepreneurship more feasible?