Clojure uses too much runtime reflection. I tried many iterations of compiling different server projects with Graal and none worked. I could get simple programs to compile with an older clojure version, but nothing with recent code.
I'd expect the tooling will improve over time. This obviously isn't an immediate solution for running Clojure in situations where cold starts matter, but in general I think many of the improvements coming to the JVM in the next few years will pay dividends for Clojure.
