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Is this data talking about a "cure" where people no longer would be labeled as having depression at all, or are we talking about clinically significant improvements/better than placebo results?



the studies (which admittedly are short-term) reflect remission - i.e., resolution of symptoms. This is a critical point: the goal is resolution of symptoms, not partial improvement.

The closest thing to a cure (for some people) can be cognitive-behavioral therapy, or long-term antidepressant treatment when indicated.




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