I haven't changed the stuff in the boxes in a while.
One box is literally the bottom of a wooden puzzle board, missing the puzzle pieces naturally, because God knows where they went a year ago, about 8 small wood blocks, and a matchbox car.
Currently my 4 year old makes that a hockey rink and the blocks are players. The car is the zamboni. Last month it was a destruction derby with towers.
Use whatever is at hand, many of the boxes don't have much else than some cotton balls, sticks, and rocks, and others are more involved.
The point is to rotate them through every once in awhile and it becomes new again. They invent new things to do with it each time it comes through.
On the occasion I've looked in on the play, you can see them fight it initially, my two year old will shuffle around the room for a while or take a quick nap, my 4 year old will lay on the bed or fuss for a bit, and within 30 minutes they'll gravitate to the box and start working it out.