Wails seems to be a software framework for creating desktop applications, where Vugu is a UI library for creating webpages.

Very different goals, even if they're both essentially "glue Go stuff to web stuff"

Wails says "framework for building desktop apps..." while the above says "Build a web front-end..."

Looks like they have rather diverse goals, except that both use go lang.

I can't comment on Wails but Vugu is for building front-end code that runs in-browser, written in Go and running via WebAssembly. You can make calls to the backend however you like, it doesn't impose much at all in this regard except as it relates to updating the UI/DOM.