Similar experience here. I had residual pain from a neck fusion and doc put me on those 800mg ibuprofen horse pills + PT. It seemed to help at first but then plateaued and didn't seem to help much. After I had been on ibuprofen for months I noticed that small cuts on my hands (typical for my line of work) were slow to heal.
One day I went to a lecture on brain research by some top neurologist at Stanford. As an aside about the difficulty of maintaining double-blind standard in actual experiments, she mentioned that she once worked on research involving NSAIDs. To mark the mice for tracking they punched coded holes in their ears but found they could tell which mice were getting NSAIDs because the holes would not heal for the treated mice whereas in untreated mice the holes would heal. I tossed the horse pills that night when I got back from the lecture and the cuts on my hands started healing normally again.
One day I went to a lecture on brain research by some top neurologist at Stanford. As an aside about the difficulty of maintaining double-blind standard in actual experiments, she mentioned that she once worked on research involving NSAIDs. To mark the mice for tracking they punched coded holes in their ears but found they could tell which mice were getting NSAIDs because the holes would not heal for the treated mice whereas in untreated mice the holes would heal. I tossed the horse pills that night when I got back from the lecture and the cuts on my hands started healing normally again.