I have still never gotten Fallout NV to run without crashing catastrophically less than 2 hours in. I've tried different machines (laptop vs. custom desktop) and several mods to fix this, but when I realized I had sunk 4 hours into it already and it was looking like an all day project I walked away and haven't come back since.
It's one of my bigger gaming disappointments, honestly, especially after constantly reading how much everyone loves it years later. I keep hoping for a remaster or something so I can run it without buying new hardware which may or may not work and/or tinkering for hours.
This doesn't help you but the PS3 version was a pretty great game - I don't remember it crashing constantly. I was sad that it would/could? not get the mod support the PC version got that I kept reading about online, but apparently that was a tradeoff.
It's one of my bigger gaming disappointments, honestly, especially after constantly reading how much everyone loves it years later. I keep hoping for a remaster or something so I can run it without buying new hardware which may or may not work and/or tinkering for hours.