Generally agree with ppl who say that searching is more important than organising. I use Alfred to search, but I think the default Finder app is quite good these days.
Most important thing is having a consistent filenaming convention. This helps you find files via search. I use 'YYMMDD_HHMM name' if I authored the file or 'YYMMDD_HHMM [sender] name' if someone emailed it to me.
Tangentially, what I'm really happy with is how I manage my web bookmarks. I don't use browser bookmarks or folders. I save bookmarks to Pinboard.in, a cloud service. Then there's a nice Alfred extension which allows me to find them (http://www.packal.org/workflow/alfred-pinboard).
Most important thing is having a consistent filenaming convention. This helps you find files via search. I use 'YYMMDD_HHMM name' if I authored the file or 'YYMMDD_HHMM [sender] name' if someone emailed it to me.
Tangentially, what I'm really happy with is how I manage my web bookmarks. I don't use browser bookmarks or folders. I save bookmarks to Pinboard.in, a cloud service. Then there's a nice Alfred extension which allows me to find them (http://www.packal.org/workflow/alfred-pinboard).