I use a native application (QuiteRSS) as my reader but for twitter I use a modified version of the twitter_search_to_rss.pl and twitter_user_to_rss.pl + TwitRSS.pm from TwitRSS.me (https://github.com/ciderpunx/twitrssme/tree/master/fcgi). The resulting xml files are saved out into my ~/www/RSS/ directory and that URL path is used in my various readers.