Since "synthetic" is basically a synonym for "artificial", I don't see why it shouldn't. Silicon is no more special than carbon.

Even beyond Si vs. C - it's really if we can just figure out how to make some semblance of the human mind using our own engineering.

Strong AI like described is pretty scary, but perhaps humans will be integrated with the tech. As this replaces our slower systems, perhaps the biggest question is what part of the mind makes us "human". If we modify that, are we still human?