Correct - the coverage number is an average across the sequenced parts of the genome. In some areas the coverage will be much higher, in others much lower.
Importantly, what is commonly called 'whole genome sequencing' is not really that. There remains ~5-8% of the genome that is (almost) impossible to sequence with current technology, and as such has no coverage. Areas with lots of repeats, centromeres, etc.
Correct - the coverage number is an average across the sequenced parts of the genome. In some areas the coverage will be much higher, in others much lower.
Importantly, what is commonly called 'whole genome sequencing' is not really that. There remains ~5-8% of the genome that is (almost) impossible to sequence with current technology, and as such has no coverage. Areas with lots of repeats, centromeres, etc.