Typescript looks interesting and increasingly appealing -- it is high on my list of tech to explore.
However, absolutist statements are not very useful... It shouldn't even need saying, but clearly large javascript projects do succeed from time to time.
"Time to time" is reductive even. Large Javascript projects succeed all the time, and have done for decades. This whole thread needs a bit of perspective, no matter what you think of Typescript, the web wasn't invented in 2015...