From Medford, OR to San Francisco along the coast, but skipped a section before Crescent City due to advice of it being dangerous to cycle through. I put some photos at #or2ca17
Cave Junction to Crescent city is a narrow two lane road with high cliffs/drops on each side, and a tunnel, with semi-trucks taking that route (I was told). I opted for a shuttle for that section after looking it up on Google StreetView - http://oregon-point.com/southwest-point/