I have the 2016 version and the only gotcha I've run into running Fedora out of the box is suspend to RAM does not work (sleep, wake, sleep, wake, sleep, wake). But it's easy to fix:
Create a file in /etc/tmpfiles.d/
-rw-r--r--. root root suspendfix.conf
w /proc/acpi/wakeup - - - - PWRB
w /proc/acpi/wakeup - - - - XHC
And one other small problem with easy work around, older kernels (Fedora 27 and older so circa kernel 4.12 and older) do not instantiate USB if the USB-C to USB-3 adapter is connected during boot. So if you boot a USB stick with one of the two USB 3.1 gen 2 ports, you'll see GRUB 2, it finds and loads the kernel and initramfs but then you end up in a rescue shell because the kernel itself can't find the stick. Workaround 1 is to boot off the powerport / USB 3.1 gen 1 (not Thunderbolt) port using a fully charged battery and install. Work around 2 is Fedora 28 which has a kernel that's working correctly, so you can use either of the USB 3.1 gen 2 ports just fine while still being plugged into power.
I have the 2016 version and the only gotcha I've run into running Fedora out of the box is suspend to RAM does not work (sleep, wake, sleep, wake, sleep, wake). But it's easy to fix:
Create a file in /etc/tmpfiles.d/ -rw-r--r--. root root suspendfix.conf
That's it. Powerbutton will still work for suspend and wake. Gory details of bisecting this and ACPI debugging with kernel devs https://bugzilla.kernel.org/show_bug.cgi?id=185521And one other small problem with easy work around, older kernels (Fedora 27 and older so circa kernel 4.12 and older) do not instantiate USB if the USB-C to USB-3 adapter is connected during boot. So if you boot a USB stick with one of the two USB 3.1 gen 2 ports, you'll see GRUB 2, it finds and loads the kernel and initramfs but then you end up in a rescue shell because the kernel itself can't find the stick. Workaround 1 is to boot off the powerport / USB 3.1 gen 1 (not Thunderbolt) port using a fully charged battery and install. Work around 2 is Fedora 28 which has a kernel that's working correctly, so you can use either of the USB 3.1 gen 2 ports just fine while still being plugged into power.