They all use it. My son has been able to mostly-sorta-kinda work the wireless keyboard since he was two and my wife has no issues using her laptop or our theater PC which remains hooked up to the TV.
Visiting parents? Sure, I have to remind my Mom how to use it every time. That happens once a year, not a real concern given the thousands of dollars I have saved. Also, you may find that you watch less TV with a setup like this assuming your someone who typically has it on in the background nearly all of the time.