> As of 2015, the long-term effects of MDMA on human brain structure and function have not been fully determined.
MDMA in itself isn't as bad as other drugs, as has been mentioned. It's the compounds that it's cut/mixed with that poses most of the immediate dangers. In fact, the therapeutic potential of MDMA is reason enough for it's rescheduling.
That's true in aggregate, but there is still obvious evidence that when taken over long periods, MDMA results in neurodegeneration, and that this is only partially reversible. Serotonergic pathways are especially effected, which is why acute MDMA use causes short-term depressive symptoms (tolerance), and long-term MDMA causes long-term depressive symptoms (neurotoxicity).
I'm not saying MDMA is as bad as other drugs, nor that it should be illegal. My cousin's uncle's daughter's brother has taken it several times, and he thinks it definitely has a lot of potential for therapy - can't attest to PTSD, but he can absolutely see it working for couple's counseling.
What I'm saying is that it shouldn't be something you can pick up for $5 at the gas station. If MDMA were legal, I would want there to be some pseudofed-like limit to how often you could purchase it (one dose every 3 months is generally considered safe), and I would also want it to be required to take the drug immediately after purchase.
> As of 2015, the long-term effects of MDMA on human brain structure and function have not been fully determined.
MDMA in itself isn't as bad as other drugs, as has been mentioned. It's the compounds that it's cut/mixed with that poses most of the immediate dangers. In fact, the therapeutic potential of MDMA is reason enough for it's rescheduling.
http://www.maps.org/research/mdma