Our current solution is for trucks to drive down the road spraying pesticides everywhere.

We know that kills far more than mosquitoes.

Except this proposal is widely accepted in the scientific community with hundreds of ecological studies behind it, where as the Four Pests was just speculation by a guy who likely never studied any modern biology.

Yes, that’s definitely a huge differentiation.

What i was using this example for, however, was the unpredictability of influencing an infinitely interconnected and complex system. In the case of the four pests, the influence was crude and especially myopic, so it makes for a wonderful example.

It is rare that the influence ends where we imagine it would. There are many possibilities for race conditions which i know i can’t even imagine.

This case it's probably being done to recent invasive species... As in the ecosystem was fine before they came, and will be fine after they're gone again.

To be fair, depending on your definition of "fine," it could be fine now and it could be fine in the middle of an ice age.

How about: the ecosystem was the way humans nostalgically preferred it before the mosquitos came, and it'll likely be the way humans nostalgically preferred it again once they're gone.

Not just mosquitoes, this one specific type of invasive mosquito. There will still be many other mosquitoes after the wolbachia thingy is done. It doesn't work on most mosquitoes