He must know his philosophy on selling is fundamentally flawed though. The high-budget computer game question (which he side stepped) is a good one. Why would you spend millions of dollars on a software product if you could only count on selling the first copy?
You could charge for the binaries, like Red Hat and XChat do. Quoting from http://xchat.org/windows/:
You may use XChat for Windows for free for 30 days. If, after this time, you would like to continue using the product, you are required to register. Registration is a one time fee of $19.99 USD (US Dollars) which can be paid using the PayPal service below.