>Reduction in LDL correlates so well with reduction in mortality (statin trials) that
Citation please.
From my other comment:
In fact, if you would be so kind as to refer to some studies where, as you say "Reduction in LDL correlates so well with reduction in mortality (statin trials)", I would be very grateful, because, afaik usually those studies found "reduction in cardiac mortality", but all-cause mortality figures are more important.
Harrison's 17th edition has an entire chapter summarizing all statin trials to date; there is a dose-response curve between LDL and mortality, with no lower limit. Or try a recent meta-analysis of statin trials looking specifically at all-cause mortality (PMID 20403481). Or see (PMID 19067719) if you want another statins + all-cause mortality meta-analysis.
In another post you pointed to one article asking about the risk of cancer in statin-treated patients. That was a scare a few years ago; now, in contrast, the NIH is funding statin trials for cancer prevention (specifically colorectal and skin cancers).
Citation please.
From my other comment:
In fact, if you would be so kind as to refer to some studies where, as you say "Reduction in LDL correlates so well with reduction in mortality (statin trials)", I would be very grateful, because, afaik usually those studies found "reduction in cardiac mortality", but all-cause mortality figures are more important.