"Being very detached from the Hollywood scene, Murray does not have an agent or manager and reportedly only fields offers for scripts and roles using a personal telephone number with a voice mailbox that he checks infrequently. This practice has the downside of sometimes preventing him from taking parts that he had auditioned for and was interested in, such as that of Sulley in Monsters, Inc, Bernard Berkman in The Squid and the Whale, Frank Ginsburg in Little Miss Sunshine and Willy Wonka in Charlie and the Chocolate Factory. He also regretted losing the chance to play Eddie Valiant in Who Framed Roger Rabbit when he heard that he was considered for the role, which he says he would have definitely accepted."
I don't think turning down major opportunities through outright neglect is ever a good habit, even for those with a surfeit.
