Clicking the same button twice in a row in rapid succession is much easier for a human to do than clicking two small buttons on different parts of the screen. A naive counter of "actions per minute" would count both things as exactly the same number of actions.
Whenever the harder action is better than the simpler one, the AI would gain an intrinsic advantage even though it's limited to the same number of APM.
Whenever the harder action is better than the simpler one, the AI would gain an intrinsic advantage even though it's limited to the same number of APM.